Cell-Free DNA (cfDNA) Testing Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2016 - 2024
"The Report Cell-Free DNA
(cfDNA) Testing Market - Global Industry Analysis, Size, Share,
Growth, Trends and Forecast 2016 - 2024 provides information on
pricing, market analysis, shares, forecast, and company profiles for
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About
Cell-Free
DNA (cfDNA) Testing Market
Cell-Free
DNA are fragments of DNA which circulate in the blood fluid and can
be utilized as valuable biomarkers. It is a new technology in which
small quantity of liquid sample (saliva, urine, or blood) from the
patient is collected to examine the freely flowing DNA. Cell-Free DNA
(cfDNA) is a noninvasive screening test used to help detect graft
rejection, identify mutations in cancer patients and detect various
chromosomal abnormalities in the fetus, in order to know the gender
of fetus. The discovery of cfDNA has opened up to new potentials in
the field of oncology, gynecology, transplantation and infectious
diseases.
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The
cell-free DNA testing market is segmented on basis of its
application, types and region. On basis of application the market is
segmented into oncology, gynecology and transplantation. By type, the
market is further segmented into donor derived cell free DNA
(ddcfDNA), circulating cell-free tumor DNA (ctDNA) and cell-free
fetal DNA (NIPT). Donor-derived cell-free DNA testing examines the
graft rejection in transplanted patient by recognizing the absence or
presence of donor DNA in the bloodstream. In ctDNA testing,
circulating tumor DNA in urine, saliva or blood of tumor patients is
examined to detect mutation. In prenatal testing, the chromosomal
abnormality is identified in the fetus by collection of blood sample
from pregnant women who carry DNA of that fetus.
The
cell-free fetal DNA market has a major share in the market due to
increased number of pregnancies following to it is the circulating
cell-free tumor DNA market and later the donor derived cell-free DNA
market. In the region wise segmentation, North America region had the
largest revenue in 2015 due to majority of tests launched and
adaptation of advanced technologies in screening techniques.
Following North America is Europe and Asia Pacific which are also the
fastest growing market due to blooming economy and improving
healthcare infrastructure and rising prevalence of diseases in these
regions. The potential of cell-free DNA
testing market has attracted many biotechnology and pharmaceutical
firms by acquiring other major firms or by launching novel tests.
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Increased
incidences of diseases like chromosomal abnormalities due to increase
in maternal age, changing lifestyle, unhealthy diet habits and rising
prevalence of cancer, also in addition to it increasing healthcare
expenditure and rising healthcare awareness are the reasons driving
the cell-free DNA market. However, there are some other factors such
as lack of skilled healthcare professionals, high test cost,
non-affordability in low income countries, ethical issues related to
genetic testing, lack of standardization, unfavorable reimbursement
policies and legal and regulatory guidelines some of the reasons
hampering the growth of the market.
Various
companies are coming up with new software’s and improved sequencing
technologies which has improved the test quality with accurate and
rapid results. Some of the leading players in cell-free DNA testing
market are Agilent Technology, Allenex AB, Biocept, Inc., Biodesix,
Inc., CareDx, Inc. Guardant Health, Inc., Illumania, Inc., Inivated
Limited, Natera, Inc., Quest Diagnostics, Roche Holdings AG,
Sequenom, Inc. and Trovagene, Inc. The global cell-free DNA testing
market is a competitive market and all the players are involved in
developing new assays by mergers and acquisitions In order to sustain
themselves in the market and maintain their market share. For
instance, Roche Holdings AG received U.S. FDA approval for its newly
launched ctDNA test Cobas which is approved for blood based genetic
tests. Roche also entered the NIPT market with acquisition of Ariosa
diagnostics. CareDx, Inc., acquired Allenex AB for its new
developments in donor derived Cell-Free DNA tests for kidney and
heart transplant patients.
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The
report offers a comprehensive evaluation of the market. It does so
via in-depth insights, understanding market evolution by tracking
historical developments, and analyzing the present scenario and
future projections based on optimistic and likely scenarios. Each
research report serves as a repository of analysis and information
for every facet of the market, including but not limited to: Regional
markets, technology developments, types, applications, and the
competitive landscape.
The
study is a source of reliable data on:
Key
market segments and sub-segments
Evolving
market trends and dynamics
Changing
supply and demand scenarios
Quantifying
market opportunities through market sizing and market forecasting
Tracking
current trends/opportunities/challenges
Competitive
insights
Opportunity
mapping in terms of technological breakthroughs
The
regional analysis covers:
North
America (U.S. and Canada)
Latin
America (Mexico, Brazil, Peru, Chile, and others)
Western
Europe (Germany, U.K., France, Spain, Italy, Nordic countries,
Belgium, Netherlands, Luxembourg)
Eastern
Europe (Poland, Russia)
Asia
Pacific (China, India, Japan, ASEAN, Australia and New Zealand)
Middle
East and Africa (GCC, Southern Africa, North Africa)
TMR
estimates the market size of various sectors using a combination of
available data on the number and revenue of companies within each
sub-sector and tiers of companies. The basic components used to
determine market size and forecast for a specific product area are
not only limited to supply-side data, but are also related to demand,
industry trends, and the economic outlook. All the above data points
are utilized to generate a statistical model targeting the sector
marketplace. More than 300 TMR analysts across the world integrate
these elements into a framework to determine the subsector market
size for a base year and then forecast growth within each market.
TMR
regularly interviews technology and business professionals as an
ongoing effort to track the latest developments within each sector.
These continuous surveys are stratified by company size and industry
segment and weighted to reflect the global market place. All data
are collected on an ongoing effort through a structured questionnaire
rolled over the web or conducted via telephones. This provides the
TMR team opportunities to request for detailed question sets, complex
skip patterns, and real-time calculations, which assists respondents
in answering questions involving numbers and percentages.
Respondents, who are interviewed as experts, are screened and
qualified based on certain criteria in addition to their
decision-making authority and the scope of activity within their
organizations.
Note:
Although care has been taken to maintain the highest levels of
accuracy in TMR’s reports, recent market/vendor-specific changes
may take time to reflect in the analysis.
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